Basic Pharmacologic principles

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10 Questions - Developed by: Leonard - Developed on: - 761 taken

Basic Pharmacologic principles

  • 1
    1. With regard to the components of pharmacokinetics p.3
    a. lipophilic drugs are most optimally absorbed through the GI tract
  • 2
    1. With regard to the components of pharmacokinetics p.3
    a. bioavailability refers to the percentage of the administered drug reaching the circulation
  • 3
    1. With regard to the components of pharmacokinetics p.3
    a. during metabolism, hydrophilic drugs get converted to more lipophilic metabolites to enable excretion
  • 4
    1. With regard to the components of pharmacokinetics p.3
    a. typically drugs must be relatively hydrophilic to enter the body by topical or oral routes
  • 5
    1. With regard to the components of pharmacokinetics p.3
    a. the first pass effect occurs prior to GI absorption via the portal vein to the liver
  • 6
    2. With regard to variables that affect absorption of drugs by oral administration p.4
    a. the impact of food on drug absorption is greater for tetracycline than for minocycline
  • 7
    1. With regard to variables that affect absorption of drugs by oral administration p.4
    a. milk reduces the absorption of tetracyclines
  • 8
    1. With regard to variables that affect absorption of drugs by oral administration p.4
    a. iron-containing products increase the absorption of tetracyclines
  • 9
    1. With regard to variables that affect absorption of drugs by oral administration p.4
    a. a relatively low gastric pH is necessary for the optimal absorption of fluconazole
  • 10
    2 With regard to variables that affect absorption of drugs by oral administration p.4
    a. antacids increase the absorption of fluoroquinolone antibiotics

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