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Neuroscience SEM 2

20 Questions - Developed by: - Developed on: 2015-05-27 - 1,640 taken

Drug addiction

1

Subcutaneous administration of drugs

Into large muscles
Through mucous membranes
Into fatty tissue

2

Drug tolerance

Jhiu
Shift in dose response curve
Feeling the effects of the drug less

3

Cross tolerance

Jdekf
Being tolerant to a drug makes you tolerant to all drugs
One drug can produce tolerance in another

4

Increasing sensitivity to drugs is known as

Drug intolerance
Drug sensitisation
Drug desensitisation

5

Drug tolerance types

Ehrwf
Sensitisation and desensitisation
Metabolic and functional

6

Metabolic tolerance

NB other is functional tolerance
Changes that reduce the reactivity of action sites
Changes that reduce the amount of drug getting to the site of action

7

Individuals suffering withdrawal effects are

Tolerant to that particular drug
Classed as drug addicts
Physically dependent

8

Two types of drug tolerance

Sensitised and conditioned
Eirhgwi
Contingent and Conditioned

9

Contingent drug tolerance

Tolerance maximally expressed when drug is taken in the same context
NB other is conditioned tolerance
Tolerance only occurs to drug effects that are actually experienced

10

Tobacco heritability estimate

10%
50%
65%

11

Alchohol heritability estimate

65%
55%
78%

12

Individuals who no longer have drugs in their systems or withdrawal symptoms are said to be

Diminished addicts
Eoruhgw
Detoxified addicts

13

Which system moderates Intracranial self stimulation?

Mesotelencephalic dopamine system
Mesocorticolimbic dopamine system
Hefhke

14

Things associated with drug addiction

Noreprinephrine and the nucleus accumbens
Nucleus accumbens and dopamine
Dopamine and Serotonin

15

Prefrontal cortex mediates

Conditional cue induced relapse
Stress induced relapse
Priming induced relapse

16

Amygdala mediates

Conditional cue induced relapse
Priming induced relapse
Stress induced relapse

17

Hypothalamus mediates

Conditional cue induced relapse
Priming induced relapse
Stress induced relapse

18

Repeated cocaine exposure

Euifhw
Facilities LTP induction in VTA dopamine neurons
Facilitates LTP induction in serotinergic neurons

19

Which opiod receptor gene can stop alcoholism eh nalextone the opioid agonist?

Asr40
Asp40
Asn40

20

Which gene is most common in people addicted to alcohol and cocaine?

A1 allele of DrD2 receptor gene
A2 allele of DRD2 receptor gene
Asp40
Asn40

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