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Neuroscience
Neuroscience SEM 2
20 Questions - Developed by:
Emma
- Developed on:
2015-05-27
- 1,640 taken
Drug addiction
1
Subcutaneous administration of drugs
Into large muscles
Through mucous membranes
Into fatty tissue
2
Drug tolerance
Jhiu
Shift in dose response curve
Feeling the effects of the drug less
3
Cross tolerance
Jdekf
Being tolerant to a drug makes you tolerant to all drugs
One drug can produce tolerance in another
4
Increasing sensitivity to drugs is known as
Drug intolerance
Drug sensitisation
Drug desensitisation
5
Drug tolerance types
Ehrwf
Sensitisation and desensitisation
Metabolic and functional
6
Metabolic tolerance
NB other is functional tolerance
Changes that reduce the reactivity of action sites
Changes that reduce the amount of drug getting to the site of action
7
Individuals suffering withdrawal effects are
Tolerant to that particular drug
Classed as drug addicts
Physically dependent
8
Two types of drug tolerance
Sensitised and conditioned
Eirhgwi
Contingent and Conditioned
9
Contingent drug tolerance
Tolerance maximally expressed when drug is taken in the same context
NB other is conditioned tolerance
Tolerance only occurs to drug effects that are actually experienced
10
Tobacco heritability estimate
10%
50%
65%
11
Alchohol heritability estimate
65%
55%
78%
12
Individuals who no longer have drugs in their systems or withdrawal symptoms are said to be
Diminished addicts
Eoruhgw
Detoxified addicts
13
Which system moderates Intracranial self stimulation?
Mesotelencephalic dopamine system
Mesocorticolimbic dopamine system
Hefhke
14
Things associated with drug addiction
Noreprinephrine and the nucleus accumbens
Nucleus accumbens and dopamine
Dopamine and Serotonin
15
Prefrontal cortex mediates
Conditional cue induced relapse
Stress induced relapse
Priming induced relapse
16
Amygdala mediates
Conditional cue induced relapse
Priming induced relapse
Stress induced relapse
17
Hypothalamus mediates
Conditional cue induced relapse
Priming induced relapse
Stress induced relapse
18
Repeated cocaine exposure
Euifhw
Facilities LTP induction in VTA dopamine neurons
Facilitates LTP induction in serotinergic neurons
19
Which opiod receptor gene can stop alcoholism eh nalextone the opioid agonist?
Asr40
Asp40
Asn40
20
Which gene is most common in people addicted to alcohol and cocaine?
A1 allele of DrD2 receptor gene
A2 allele of DRD2 receptor gene
Asp40
Asn40
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