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Neuroscience SEM 2

20 Questions - Developed by: Emma - Developed on: 2015-05-27 - 1,608 taken

Drug addiction

1

Subcutaneous administration of drugs

Into large muscles
Through mucous membranes
Into fatty tissue

2

Drug tolerance

Feeling the effects of the drug less
Jhiu
Shift in dose response curve

3

Cross tolerance

One drug can produce tolerance in another
Being tolerant to a drug makes you tolerant to all drugs
Jdekf

4

Increasing sensitivity to drugs is known as

Drug intolerance
Drug desensitisation
Drug sensitisation

5

Drug tolerance types

Metabolic and functional
Ehrwf
Sensitisation and desensitisation

6

Metabolic tolerance

Changes that reduce the reactivity of action sites
NB other is functional tolerance
Changes that reduce the amount of drug getting to the site of action

7

Individuals suffering withdrawal effects are

Classed as drug addicts
Tolerant to that particular drug
Physically dependent

8

Two types of drug tolerance

Contingent and Conditioned
Sensitised and conditioned
Eirhgwi

9

Contingent drug tolerance

Tolerance maximally expressed when drug is taken in the same context
Tolerance only occurs to drug effects that are actually experienced
NB other is conditioned tolerance

10

Tobacco heritability estimate

50%
65%
10%

11

Alchohol heritability estimate

78%
55%
65%

12

Individuals who no longer have drugs in their systems or withdrawal symptoms are said to be

Detoxified addicts
Diminished addicts
Eoruhgw

13

Which system moderates Intracranial self stimulation?

Mesocorticolimbic dopamine system
Hefhke
Mesotelencephalic dopamine system

14

Things associated with drug addiction

Nucleus accumbens and dopamine
Noreprinephrine and the nucleus accumbens
Dopamine and Serotonin

15

Prefrontal cortex mediates

Stress induced relapse
Conditional cue induced relapse
Priming induced relapse

16

Amygdala mediates

Conditional cue induced relapse
Stress induced relapse
Priming induced relapse

17

Hypothalamus mediates

Stress induced relapse
Conditional cue induced relapse
Priming induced relapse

18

Repeated cocaine exposure

Facilitates LTP induction in serotinergic neurons
Euifhw
Facilities LTP induction in VTA dopamine neurons

19

Which opiod receptor gene can stop alcoholism eh nalextone the opioid agonist?

Asr40
Asn40
Asp40

20

Which gene is most common in people addicted to alcohol and cocaine?

A2 allele of DRD2 receptor gene
Asn40
A1 allele of DrD2 receptor gene
Asp40

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