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Neuroscience SEM 2

20 Questions - Developed by: - Developed on: 2015-05-27 - 1,664 taken

Drug addiction

1

Subcutaneous administration of drugs

Through mucous membranes
Into large muscles
Into fatty tissue

2

Drug tolerance

Shift in dose response curve
Feeling the effects of the drug less
Jhiu

3

Cross tolerance

One drug can produce tolerance in another
Jdekf
Being tolerant to a drug makes you tolerant to all drugs

4

Increasing sensitivity to drugs is known as

Drug desensitisation
Drug intolerance
Drug sensitisation

5

Drug tolerance types

Ehrwf
Sensitisation and desensitisation
Metabolic and functional

6

Metabolic tolerance

Changes that reduce the amount of drug getting to the site of action
NB other is functional tolerance
Changes that reduce the reactivity of action sites

7

Individuals suffering withdrawal effects are

Classed as drug addicts
Tolerant to that particular drug
Physically dependent

8

Two types of drug tolerance

Contingent and Conditioned
Eirhgwi
Sensitised and conditioned

9

Contingent drug tolerance

Tolerance only occurs to drug effects that are actually experienced
NB other is conditioned tolerance
Tolerance maximally expressed when drug is taken in the same context

10

Tobacco heritability estimate

10%
65%
50%

11

Alchohol heritability estimate

78%
55%
65%

12

Individuals who no longer have drugs in their systems or withdrawal symptoms are said to be

Eoruhgw
Detoxified addicts
Diminished addicts

13

Which system moderates Intracranial self stimulation?

Hefhke
Mesotelencephalic dopamine system
Mesocorticolimbic dopamine system

14

Things associated with drug addiction

Noreprinephrine and the nucleus accumbens
Dopamine and Serotonin
Nucleus accumbens and dopamine

15

Prefrontal cortex mediates

Priming induced relapse
Conditional cue induced relapse
Stress induced relapse

16

Amygdala mediates

Priming induced relapse
Conditional cue induced relapse
Stress induced relapse

17

Hypothalamus mediates

Stress induced relapse
Conditional cue induced relapse
Priming induced relapse

18

Repeated cocaine exposure

Facilitates LTP induction in serotinergic neurons
Euifhw
Facilities LTP induction in VTA dopamine neurons

19

Which opiod receptor gene can stop alcoholism eh nalextone the opioid agonist?

Asr40
Asn40
Asp40

20

Which gene is most common in people addicted to alcohol and cocaine?

Asp40
A1 allele of DrD2 receptor gene
A2 allele of DRD2 receptor gene
Asn40

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