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Neuroscience
Neuroscience SEM 2
20 Questions - Developed by:
Emma
- Developed on:
2015-05-27
- 1,664 taken
Drug addiction
1
Subcutaneous administration of drugs
Through mucous membranes
Into large muscles
Into fatty tissue
2
Drug tolerance
Shift in dose response curve
Feeling the effects of the drug less
Jhiu
3
Cross tolerance
One drug can produce tolerance in another
Jdekf
Being tolerant to a drug makes you tolerant to all drugs
4
Increasing sensitivity to drugs is known as
Drug desensitisation
Drug intolerance
Drug sensitisation
5
Drug tolerance types
Ehrwf
Sensitisation and desensitisation
Metabolic and functional
6
Metabolic tolerance
Changes that reduce the amount of drug getting to the site of action
NB other is functional tolerance
Changes that reduce the reactivity of action sites
7
Individuals suffering withdrawal effects are
Classed as drug addicts
Tolerant to that particular drug
Physically dependent
8
Two types of drug tolerance
Contingent and Conditioned
Eirhgwi
Sensitised and conditioned
9
Contingent drug tolerance
Tolerance only occurs to drug effects that are actually experienced
NB other is conditioned tolerance
Tolerance maximally expressed when drug is taken in the same context
10
Tobacco heritability estimate
10%
65%
50%
11
Alchohol heritability estimate
78%
55%
65%
12
Individuals who no longer have drugs in their systems or withdrawal symptoms are said to be
Eoruhgw
Detoxified addicts
Diminished addicts
13
Which system moderates Intracranial self stimulation?
Hefhke
Mesotelencephalic dopamine system
Mesocorticolimbic dopamine system
14
Things associated with drug addiction
Noreprinephrine and the nucleus accumbens
Dopamine and Serotonin
Nucleus accumbens and dopamine
15
Prefrontal cortex mediates
Priming induced relapse
Conditional cue induced relapse
Stress induced relapse
16
Amygdala mediates
Priming induced relapse
Conditional cue induced relapse
Stress induced relapse
17
Hypothalamus mediates
Stress induced relapse
Conditional cue induced relapse
Priming induced relapse
18
Repeated cocaine exposure
Facilitates LTP induction in serotinergic neurons
Euifhw
Facilities LTP induction in VTA dopamine neurons
19
Which opiod receptor gene can stop alcoholism eh nalextone the opioid agonist?
Asr40
Asn40
Asp40
20
Which gene is most common in people addicted to alcohol and cocaine?
Asp40
A1 allele of DrD2 receptor gene
A2 allele of DRD2 receptor gene
Asn40
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